
Matrixome是指与细胞外基质(ECM)相关的蛋白质和蛋白质复合物的集合,这些成分在细胞外基质中形成复杂的网络结构,对细胞的生长、迁移和分化等生物学过程起着重要作用。Matrixome的研究有助于理解细胞与ECM之间的相互作用,以及这些相互作用在疾病发生和发展中的作用12。
Matrixome主要包括以下几类蛋白质和复合物:
Matrixome在医学研究中有着广泛的应用,特别是在癌症、组织修复和再生医学等领域。例如:

Characteristics: iMatrix-511 is a highly pure and refined product of Laminin-511 E8 fragment developed by incorporating genes of human Laminin-511 E8 domains into CHO-S cells.

Characteristics: This is a highly pure and refined product of Laminin-511 E8 fragment extracted and refined from a silkworm cocoon in which genes of human Laminin-511 E8 domains have been incorporated
“iMatrix-511”和“iMatrix-511 silk”是用于细胞培养的重组人层粘连蛋白-511 E8片段。以下是层粘连蛋白-511 E8片段在胚胎干细胞(ES)/诱导多能干细胞(iPS细胞)和间充质干细胞(MSC)上可能具有的特性:
Click here for the extended culture protocol for hES/hiPS cells using iMatrix-511. (This link takes you to an external site.) \ Click here for the video for the passage procedure for hES/hiPS cells using iMatrix-511. (This link takes you to an external site.)